INTEGRATIVE ANALYSIS OF BULK AND SINGLE-CELL RNA-SEQ REVEALS THE MOLECULAR CHARACTERIZATION OF THE IMMUNE MICROENVIRONMENT AND OXIDATIVE STRESS SIGNATURE IN MELANOMA

Integrative analysis of bulk and single-cell RNA-seq reveals the molecular characterization of the immune microenvironment and oxidative stress signature in melanoma

Background: The immune microenvironment and oxidative stress of melanoma show significant heterogeneity, which affects tumor growth, invasion and treatment response.Single-cell and bulk RNA-seq data were used to explore the heterogeneity of the immune microenvironment and oxidative stress of melanoma.Methods: The R grapevine colour saree package Se

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Identifying and documenting the Traras mountains(Northwest-Algeria) rural heritage architectural features: an architectural survey.

In the extreme northwest of the Algerian territory the Traras Mountain the vernacular architecture of the houses is facing 2000 dodge dakota catalytic converter natural and human threats.with its loss, a synthesis of traditional rural life, imminent.This article is aimed at identifying and recording the characteristics of traditional vernacular arc

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Expression of an Efficient Selection Marker Out of a Duplicated Site in the ITRs of a Modified Vaccinia Virus Ankara (MVA)

Background/Objectives: Poxviruses are large DNA viruses that replicate in the host cytoplasm without a nuclear phase.As vaccine vectors, they can package and express large recombinant cassettes from different positions of their genomic core region.We present a comparison between wildtype modified vaccinia Ankara (MVA) and isolate CR19, which has si

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